Zeiss
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The Zeiss LSM 880 is a confocal laser scanning microscope designed for fluorescence imaging of fixed and live samples. The Zeiss LSM 880 features a 32-channel GaAsP Airyscan detector for high-resolution imaging with spectral detection. The Zeiss LSM 880 supports laser lines at 405 nm, 458/488/514 nm, 561 nm, and 633 nm, with additional lines for ablation and photoactivation.[1][2][3]

The LSM 880 is controlled by the ZEN software (black edition). The system includes a set of laser lines: 405 nm (30 mW), multiline 458/488/514 nm (25 mW), 561 nm (20 mW), and 633 nm (5 mW). Detectors comprise two photomultiplier tubes, one GaAsP detector, and the Airyscan detector (32 GaAsP). The Airyscan detector improves resolution and signal-to-noise ratio.[3][1]
The system supports applications such as fixed-sample imaging, live-cell time-lapse experiments, and three-dimensional reconstruction. The Airyscan module provides enhanced resolution suitable for quantitative live-cell experiments. The 32-channel spectral detector allows simultaneous acquisition and on-the-fly unmixing of multiple fluorophores.[1][3]
| Designation | Generation | Vintage | Changes | Source |
|---|---|---|---|---|
| LSM 880 NLO | — | — | — | manualslib.com[5] |
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The LSM 880 is equipped with laser lines at 405 nm (30 mW), a multiline argon laser (458/488/514 nm, 25 mW), 561 nm (20 mW), and 633 nm (5 mW).[3]
The LSM 880 can achieve 19 frames per second at a 512 x 512 pixel image resolution.[3]
The following facts about the LSM 880 are absent from this record as of this revision. First-hand knowledge or a citation closes a gap; every submission is reviewed before publication.
No publicly documented production dates or lifecycle milestones (introduction, end of production, EOL) for the LSM 880 are on record.
Answerable by: OEM historical records or a trade-press announcement
The control-system platform and OS era of the LSM 880 are not on record.
Answerable by: an engineer who operated it or OEM installation records
No publicly documented failure modes or field errata for the LSM 880 are on record.
Answerable by: a field service engineer, process engineer, or maintenance technician
The process node or technology generation of the LSM 880 is not on record.
Answerable by: an OEM datasheet or a fab qualification report
No publicly documented compatible parts, consumables, or accessories for the LSM 880 are on record.
Answerable by: an OEM parts catalog or a service engineer
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Last updated Oct 1, 2026.